Complete GNC Women's Ultra Mega Menopause Review: Pros & Cons

Effectiveness: (3.8/5)

Safety: (3/5)

Cost-benefit: (3.5/5)

Total: (3.4/5)

What is GNC Women's Ultra Mega® Menopause?

GNC Women's Ultra Mega® Menopause is a Vitapak® Program that helps women find relief from common menopause symptoms – night sweats and hot flashes – as well as supports heart and bone health. This product provides women with menopause supplements as well as multivitamins.

Complete GNC Women's Ultra Mega Menopause Review: Pros & Cons

Pros & Cons

Company Snapshot


80+ years in business

Money-back guarantee

Customer support

  • 1-888-462-2548

Social networks:

Effectiveness 3.8 of 5

Over 50 positive reviews of GNC Women's Ultra Mega® Menopause on Amazon and company website

/ Claimed efficacy for women going through the menopausal transition. Results will vary.

No clinical research on company's site proving product effectiveness

Safety 3 of 5

Does NOT contain gluten, yeast, artificial colors, or artificial flavors

Company does not mention short-term or long-term side effects

Not recommended for women who are pregnant, nursing, or may become pregnant

Cost-benefit 3.5 of 5

Company has been in business for almost a century, increasing credibility

/ OK cost benefit: considering price, variety of ingredients, and customer satisfaction

Price around $45 for a 1-month supply (via Amazon); but can be considered 2-for-1 with multivitamins 

Score: 3.4 out of 5.0

My Conclusions:

GNC is by far one of the oldest standing companies I have reviewed with roots dating back to 1935. Their money-back guarantee is good for 30 days from the order date and includes a full refund of the purchase price, minus the cost of shipping and handling. Just return the unused portion of the product with the receipt. In general, this seems like an effective supplement plan strictly because it helps women receive their daily multivitamins while combating menopause symptoms at the same time. However, as I have mentioned with other supplements, the use of what I would consider unnecessary fillers - such as sucralose and maltodextrin - knocks this product down a notch or two in my book in terms of healthiness. Also, some women may be turned off by the number of pills you have to take each day to receive the full benefits of this product. Since there are four, different types of pills, a woman should take seven pills daily. Four are multivitamin pills. Moreover, GNC should be transparent and mention possible short and long-term side effects that could happen when taking these pills.

For more information on GNC Women's Ultra Mega® Menopause, please visit the product through the company's home page here:

My Tips for Improvement:

  • Conduct clinical trials proving effectiveness
  • Possibly reduce number of pills needed to take
  • List side effects on company website

GNC Women's Ultra Mega Menopause Quick Fact Sheet

GNC Women's Ultra Mega Menopause Ingredients and Supplement Facts
GNC Women's Ultra Mega® Menopause Ingredients

Women's Ultra Mega Bone Density without Iron and Iodine
Main: Vitamin A, C, D, E, K, B-1, B-2, B-6, B-12; niacin, folic acid, biotin, pantothenic acid, calcium, magnesium, zinc, selenium, copper, manganese, chromium, molybdenum, MBP, alpha-Lipoic Acid, choline, inositol, green tea leaf extract, cranberry concentrate, silica, boron, lutemax 2020TM lutein, lycopene, zeaxanthin, astaxanthin, vanadium
Other: Cellulose, titanium dioxide, carmine color, natural vanilla flavor, vegetable acetoglycerides, sucralose

Menopause Formula
Main: Black cohosh root extract, soy isoflavone concentrate
Other: Cellulose, gelatin, maltodextrin

Fish Oil
Other: Fish body oil, gelatin, glycerin, natural lemon flavor, rosemary leaf extract, vitamin E

Evening Primrose Oil 1300
Other: Gelain, glycerin, enteric coating (cellulose, sodium alginate, medium chain triglycerides, oleic and stearic acid)

How GNC Women's Ultra Mega® Menopause Works

Each of the supplements in GNC Women's Ultra Mega® Menopause box is designed to support a woman's overall health. For example, the Women's Ultra Mega® Bone Density formula includes vitamins and minerals designed specifically to emphasize the key nutrients for bone health and natural bone building. It is also enhanced with cell-protecting antioxidant nutrients involved in the formation of the bone matrix.


As a dietary supplement, take the contents of one pack every day with food. Each of the pills has different contraindications. Also, it is important to check with a doctor before use if you are taking medication or have a medical condition. You may have to discontinue use of this product two week prior to surgery. Store in a cool, dry place.

Side Effects of GNC Women's Ultra Mega® Menopause

GNC does not mention any side effects from taking any of the supplements in this menopause supplement pack, nor are there reviews on Amazon or the company website mentioning any. (More women mention the bad smell and taste more than anything.) However, from outside research, I see that high doses of black cohosh can cause headaches, lightheadedness, uterine contractions, joint pain, slowed heart rate, lower blood pressure, and more. Black cohosh is not recommended for use more than six months at a time.

Where to Buy GNC Women's Ultra Mega® Menopause

GNC Women's Ultra Mega® Menopause is available for purchase through GNC's official website ( as well as on Amazon. They may also be available in GNC stores nationwide.

Anita Myers By Anita Myers, Expert Reviewer | Updated Jul 25, 2018

I am truly passionate about helping others find the path to better health, wellness, and spirituality through yoga. I blog at Anita's Wellness Journey.


  • Amazon,
  • Cancer Research UK. (2015). Black cohosh. Retrieved March 20, 2018, from
  • GNC,

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